What You Need to Know About Oclacitinib (Apoquel)

What is oclacitinib? Why was it prescribed to my pet?
Oclacitinib is a medication used to control itching associated with various skin allergies, including flea, food and environmental allergies. 

Oclacitinib has only been formally evaluated in dogs. Although it has been used safely in cats, this should only be performed under close supervision from a veterinarian.  

What forms are available?
Oclacitinib is available in tablet forms, which are given by mouth. Tablets may be given with or without food.

Tablet forms:
•    Apoquel (3.6mg, 5.4mg, 16mg)

Oclacitinib, sold under the brand name Apoquel, is available in tablets of three different strengths.

What side effects are there?
Side effects are usually limited to mild vomiting, diarrhoea or appetite loss. These are often self-limiting and not a cause for concern unless they are severe, worsen, or continue over a long period.

Oclacitinib may increase your pet’s susceptibility to infection. Contact your veterinarian if you notice any of the following:
•    Fever
•    Rash
•    Coughing 
•    Lethargy 
•    Frequent, painful and/or bloody urination
•    Any new lumps on your pet, or enlargement of existing lumps

 
When should this medication be used very carefully?
Your veterinarian may take extra precautions if your pet:
•    Has an ongoing infection or parasite infestation
•    Has cancer, or a history of cancer
•    Is taking medications that suppress the immune system

Precautions may include measures such as closer monitoring or adjustments to medication doses. For advice specific to your pet, please consult your veterinarian.

When should this medication not be used?
Your pet should not receive oclacitinib if they:
•    Are allergic to it
•    Are under 12 months of age
•    Are pregnant, breastfeeding, or being used for breeding
•    Have a severe infection such as pneumonia

What monitoring is required for pets on oclacitinib?
It is important to take your veterinarian’s advice and bring your pet for rechecks as needed.

Your veterinarian may wish to monitor:
•    Your pet’s itch level
•    For any signs of infection or parasite infestation
•    For any new lumps or enlargement of existing ones
•    Baseline blood and urine testing results

Storage and safety
Wash your hands immediately after handling this medication. 

Keep all medications out of reach of children and pets. Oclacitinib should be stored in a cool, dry place at room temperature.

If you miss a dose, give it as soon as you remember. If it is close to the time of your pet’s next scheduled dose, skip the missed dose and give the scheduled one. Afterwards, return to your pet’s regular dosing regimen.

Never give a double dose, even if you miss a dose. Contact your pet’s veterinarian if you know or suspect that your pet has received an overdose.